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phosphoexplorer array  (Full Moon BioSystems)

 
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    Full Moon BioSystems phosphoexplorer array
    Phosphoexplorer Array, supplied by Full Moon BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/phosphoexplorer array/product/Full Moon BioSystems
    Average 90 stars, based on 1 article reviews
    phosphoexplorer array - by Bioz Stars, 2026-04
    90/100 stars

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    (A) Phosphoprotein changes analyzed by <t>PhosphoExplorer</t> array in muscle satellite cells (SCs) transfected with AT2R or control siRNA, followed by induction of differentiation for 2 days. Log2 fold change values of AT2R siRNA-transfected cells compared to control are shown, with increased phosphorylation in red and decreased phosphorylation in blue. (B, C) IPA Canonical Pathway analysis (B) and Diseases and Functions Annotations (C) for the phosphoprotein changes with absolute log2 fold change values over 1 (i.e. >2 fold change). Bars indicate -log 10 p-value, and lines show the ratio of the proteins that were changed among the proteins associated with each pathway. The red and blue colors of the bar chart indicate activation z-score, and only the pathways with absolute z-scores higher than 2 (i.e. considered statistically significant). (D) Changes in phosphorylation levels in GSK3β (Ser216 and Ser9), and β-catenin (Tyr654, Thr41/Ser45, Ser37, Ser33 and Tyr489).
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    (A) Phosphoprotein changes analyzed by PhosphoExplorer array in muscle satellite cells (SCs) transfected with AT2R or control siRNA, followed by induction of differentiation for 2 days. Log2 fold change values of AT2R siRNA-transfected cells compared to control are shown, with increased phosphorylation in red and decreased phosphorylation in blue. (B, C) IPA Canonical Pathway analysis (B) and Diseases and Functions Annotations (C) for the phosphoprotein changes with absolute log2 fold change values over 1 (i.e. >2 fold change). Bars indicate -log 10 p-value, and lines show the ratio of the proteins that were changed among the proteins associated with each pathway. The red and blue colors of the bar chart indicate activation z-score, and only the pathways with absolute z-scores higher than 2 (i.e. considered statistically significant). (D) Changes in phosphorylation levels in GSK3β (Ser216 and Ser9), and β-catenin (Tyr654, Thr41/Ser45, Ser37, Ser33 and Tyr489).

    Journal: bioRxiv

    Article Title: Angiotensin II Type 2 Receptor Potentiates Skeletal Muscle Satellite Cell Differentiation via the GSK3β/β-catenin Pathway

    doi: 10.1101/2022.09.30.510328

    Figure Lengend Snippet: (A) Phosphoprotein changes analyzed by PhosphoExplorer array in muscle satellite cells (SCs) transfected with AT2R or control siRNA, followed by induction of differentiation for 2 days. Log2 fold change values of AT2R siRNA-transfected cells compared to control are shown, with increased phosphorylation in red and decreased phosphorylation in blue. (B, C) IPA Canonical Pathway analysis (B) and Diseases and Functions Annotations (C) for the phosphoprotein changes with absolute log2 fold change values over 1 (i.e. >2 fold change). Bars indicate -log 10 p-value, and lines show the ratio of the proteins that were changed among the proteins associated with each pathway. The red and blue colors of the bar chart indicate activation z-score, and only the pathways with absolute z-scores higher than 2 (i.e. considered statistically significant). (D) Changes in phosphorylation levels in GSK3β (Ser216 and Ser9), and β-catenin (Tyr654, Thr41/Ser45, Ser37, Ser33 and Tyr489).

    Article Snippet: The PhosphoExplorer Antibody Array (Cat# PEX100, Full Moon BioSystems) contains 1,318 site-specific and phospho-specific antibodies, each of which has two replicates.

    Techniques: Transfection, Activation Assay